Malarone

 
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Atovaquone/proguanil
12 Tablets

What Is Malarone

Malarone is an oral antimalarial medication that prevents malaria when traveling to areas at risk of malaria infections. Mosquito bites cause the disease. Malaria causes fever, vomiting, and even headaches. Malarone is swallowed before, during, and after visiting malaria-prone places to prevent infections by the four species of plasmodium parasites. GlaxoSmithKline Company manufactures the prescription drug. It is taken once daily, 1-2 days before travel. The treatment should continue until one week after returning.

Product supplied may be from a different manufacturer

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Description

How Does Malarone Work?

Malarone tablets contain two active ingredients, proguanil hydrochloride and atovaquone. Malaria occurs when the plasmodium parasite enters the bloodstream and starts to reproduce. Proguanil works by inhibiting the parasite's ability to reproduce. Proguanil blocks the action of the dihydrofolate reductase enzyme that helps the parasite to reproduce and multiply. It prevents the formation of any new genetic material forming within the parasite, inhibiting reproduction. Atovaquone works similarly to proguanil. It hinders the production of new genetic material from inside the malaria parasite, resulting in its inability to reproduce.

Warnings

Malarone Warnings

Malarone is unsuitable for you if you:

  • Are allergic to the ingredients.
  • Have liver or kidney problems.
  • Are pregnant or breastfeeding.

Directions

How to Take Malarone

  • You should take one tablet every day at roughly the same time daily.
  • Take 1 or 2 days before entering a high-risk zone and continue for seven days after leaving the topical area.
  • Swallow Malarone with or after food or milk.
  • Malarone remains effective with a moderate alcohol intake.
  • In the event of vomiting within 1 hour of taking Malarone, repeat the dose.

Ingredients

Malarone Ingredients

Malarone tablets contain two active ingredients Proguanil Hydrochloride and Atovaquone. Each capsule contains poloxamer 188, microcrystalline cellulose, hydroxypropyl cellulose, povidone K30, sodium starch glycolate (Type A), and magnesium stearate. The coating is made of hypromellose, titanium dioxide (E171), and iron oxide red (E172), macrogol 400, and polyethylene glycol 8000.

Side Effects

Side Effects of Using Malarone

When used to prevent malaria, Malarone tablets rarely cause side effects. If you experience any, the side effects include:

  • Coughing.
  • Diarrhoea.
  • Dizziness.
  • Headache.
  • Loss of appetite.
  • Mouth sores.
  • Nausea.
  • Stomach pain.
  • Vomiting.
  • Weakness.